Technology: From Protein Flow to Clear Guidance

The Circulatory Insight

At the core of our approach is a physiological constant:

Every minute, 250 grams of soluble proteins circulate through 3 liters of plasma in your 5 liters of blood, reaching every organ in your body.

These proteins, primarily albumin, globulins, and fibrinogen, are not just structural or metabolic agents. They are messengers, sensors, and responders in a tightly regulated system of health. Their thermal behavior reflects how well this system is functioning.

Through TLB, we assess their thermostability, uncovering imbalances long before they present as symptoms.

Smart Interpretation, Personalized Results

The TLB profile is a live snapshot of your internal health. By applying controlled heat to a small blood sample, we capture how serum proteins unfold and interact, producing a unique molecular fingerprint shaped by systemic processes.

These thermal signatures are interpreted by our proprietary AI Agent Neural Network, trained on a large, age-stratified dataset encompassing both healthy baselines and a wide range of health conditions.

If your TΔA is positive, it indicates signs of accelerated biological aging. But HΔ∂eS doesn’t stop at the number. Our system deconstructs the signal into seven domain-specific coefficients, identifying the likely physiological contributors to that shift:

  • ∂n — Neurological function

  • ∂c — Cardiovascular health

  • ∂a — Immune and autoimmune activity

  • ∂e — Endocrine and metabolic stress

  • ∂o — Oncological (cancer-related) signatures

  • ∂p — Pulmonary function

  • ∂i — Systemic infection or inflammation markers

Each attribute is weighted not only by its individual signal strength, but also by two crucial contextual factors:

  • Your chronological age

  • The typical age of onset for each physiological domain

This age-aware model reflects a key insight:

The same signal may imply very different biological meanings in a 28-year-old vs. a 68-year-old.

That’s why our system performs dynamic, context-specific interpretation, delivering two key outputs:

  • A global TΔA score

  • Including the category-weighted contributions to the shift

  • And consequent health guidance to follow up

If your TΔA is negative, it suggests you are biologically younger than your chronological age. Your current lifestyle, resilience, or interventions may be promoting healthy aging. Stay the course—and use HΔ∂eS to track how this advantage evolves over time. All your attributes cluster within the ∂healthiness zone.

If your TΔA is near zero, your biological and chronological ages are aligned. This is a good baseline—but also the point where early biological deviations may begin. Return regularly to detect subtle but actionable changes as they emerge.

If your TΔA is positive, the attribute profile reveals which physiological systems are most affected. This layered insight enables HΔ∂eS to go beyond detection—providing a personalized biological profile that informs:

  • What to explore

  • What to adjust

  • What to monitor

And because these interpretations include functional biological pathways, HΔ∂eS also supports personalized lifestyle recommendations and evidence-based clinical guidance—grounded in your biology today, not in a probability from the past.

Rather than delivering a static result, HΔ∂eS provides actionable insight, a clear path to understanding and improving your biological resilience.

This is visualized through both a clear “ruler” scale and a pie chart-style insight map, the ΔAge Profile, showing which systems are contributing most to your biological aging, pointing to possible contributors and offering context for next steps.

A single scalar number becomes a starting point for deeper understanding, not just of aging, but of how and why.

You get:

  • A drop of blood

  • An hour-long scan

  • One clear trajectory

All without invasive procedures, guesswork, or diagnostic labels.

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